SEMINAR: CMCA Seminar Series: "Watching a gene move around inside the nucleus: dynamics of living chromatin"

Associate Professor Mylne will describe a system that he established which allows the monitoring of the physical position of a gene within a nucleus by confocal microscopy. He will illustrate its use to monitor the dynamic changes in gene position for one particular Arabidopsis gene as it gets silenced by low temperature. The system allows monitoring a single gene's position in live whole plants.

Assoc. Prof. Mylne (PhD, Botany) worked at the John Innes Centre (2001-2005), using molecular genetics to study proteins that accelerate flowering in response to prolonged cold (vernalization). In 2006 he moved to the Division of Chemistry & Structural Biology at The Institute for Molecular Bioscience (IMB, UQ) where he held a QEII Fellowship (2008-2012) and was the inaugural John S. Mattick Fellow (2010-2012). In 2013 he joined the faculty at The University of Western Australia and took up an ARC Future Fellowship in the School of Chemistry & Biochemistry and The ARC Centre of Excellence in Plant Energy Biology. His research interests are protein evolution and the molecular mechanisms underlying the biosynthesis of bioactive peptides.